ANTI-N3PGLU AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF

The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are admi...

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Main Authors IRIZARRY, Michael Carl, DEMATTOS, Ronald Bradley
Format Patent
LanguageEnglish
French
German
Published 19.07.2023
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Abstract The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are administered an induction dose of 10 to 60 mg/kg of an anti-N3pGlu Aβ antibody for a period of 6 months or less.
AbstractList The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are administered an induction dose of 10 to 60 mg/kg of an anti-N3pGlu Aβ antibody for a period of 6 months or less.
Author IRIZARRY, Michael Carl
DEMATTOS, Ronald Bradley
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DocumentTitleAlternate ANTICORPS ANTI-PEPTIDE BÊTA-AMYLOÏDE N3PGLU ET LEURS UTILISATIONS
ANTI-N3PGLU AMYLOID BETA PEPTID ANTIKÖRPER UND DEREN VERWENDUNG
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RelatedCompanies Eli Lilly and Company
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Snippet The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title ANTI-N3PGLU AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF
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