METHOD OF PRODUCING A RECOMBINANT PROTEIN

The present invention relates to a recombinant signal sequence derived from E. coli. The invention also relates to a fusion protein comprising the signal sequence, a recombinant protein and methods of producing the recombinant protein. The recombinant signal sequence can be used to provide a method...

Full description

Saved in:
Bibliographic Details
Main Authors LEWIS, Alan Peter, LEWIS, William John Kenneth, HOARE, Michael, MCINALLY, Adam Daniel, UDEN, Mark, FINKA, Gary Brian, VOULGARIS, Ioannis, EMMINS, Robyn Alexandra
Format Patent
LanguageEnglish
French
German
Published 13.03.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

Abstract The present invention relates to a recombinant signal sequence derived from E. coli. The invention also relates to a fusion protein comprising the signal sequence, a recombinant protein and methods of producing the recombinant protein. The recombinant signal sequence can be used to provide a method for controlling the viscosity of the fermentation, and/or controlling basal (pre-induction) expression of the recombinant protein.
AbstractList The present invention relates to a recombinant signal sequence derived from E. coli. The invention also relates to a fusion protein comprising the signal sequence, a recombinant protein and methods of producing the recombinant protein. The recombinant signal sequence can be used to provide a method for controlling the viscosity of the fermentation, and/or controlling basal (pre-induction) expression of the recombinant protein.
Author LEWIS, William John Kenneth
MCINALLY, Adam Daniel
FINKA, Gary Brian
HOARE, Michael
VOULGARIS, Ioannis
EMMINS, Robyn Alexandra
UDEN, Mark
LEWIS, Alan Peter
Author_xml – fullname: LEWIS, Alan Peter
– fullname: LEWIS, William John Kenneth
– fullname: HOARE, Michael
– fullname: MCINALLY, Adam Daniel
– fullname: UDEN, Mark
– fullname: FINKA, Gary Brian
– fullname: VOULGARIS, Ioannis
– fullname: EMMINS, Robyn Alexandra
BookMark eNrjYmDJy89L5WTQ9HUN8fB3UfB3UwgI8ncJdfb0c1dwVAhydfb3dfL0c_QLAYmHuHr68TCwpiXmFKfyQmluBgU31xBnD93Ugvz41OKCxOTUvNSSeNcAYxNTIxNLM0dDYyKUAADD3iWt
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate VERFAHREN ZUR HERSTELLUNG EINES REKOMBINANTEN PROTEINS
PROCÉDÉ DE PRODUCTION D'UNE PROTÉINE RECOMBINANTE
ExternalDocumentID EP3452496A1
GroupedDBID EVB
ID FETCH-epo_espacenet_EP3452496A13
IEDL.DBID EVB
IngestDate Fri Jul 19 14:24:33 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
German
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_EP3452496A13
Notes Application Number: EP20170725188
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190313&DB=EPODOC&CC=EP&NR=3452496A1
ParticipantIDs epo_espacenet_EP3452496A1
PublicationCentury 2000
PublicationDate 20190313
PublicationDateYYYYMMDD 2019-03-13
PublicationDate_xml – month: 03
  year: 2019
  text: 20190313
  day: 13
PublicationDecade 2010
PublicationYear 2019
RelatedCompanies GlaxoSmithKline Intellectual Property Development Limited
RelatedCompanies_xml – name: GlaxoSmithKline Intellectual Property Development Limited
Score 3.185116
Snippet The present invention relates to a recombinant signal sequence derived from E. coli. The invention also relates to a fusion protein comprising the signal...
SourceID epo
SourceType Open Access Repository
SubjectTerms BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Title METHOD OF PRODUCING A RECOMBINANT PROTEIN
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190313&DB=EPODOC&locale=&CC=EP&NR=3452496A1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NS8MwFH-MKepNp-L8IgcpeCja9cP2MKRNUluhSSmd7Dba2sEu23AV_31fSje96C28QL7Ie7_3S_JeAO4e52VhoqOhG6Vb6xZiiF66bqWPPNtEvFbbSsU7J8KJJtbr1J72YLGNhWnzhH61yRFRoyrU96a11-ufQyzWvq3cPJQLFK2ew3zMtI4dI7qZhqmxYMxTySTVKMWSJjI01jYSDcdHorSnvGiVZp-_BSooZf0bUcJj2E-xsWVzAr16OYBDuv14bQAHSXffjcVO9TancJ_wPJKMyJCkmWQTGosX4pOMU5kEsfBFruQ5j8UZkJDnNNKxz9lufjOe7kZnnkMfaX99AeQJNa0oavfdQ5elQBo3R6rnVlZZGZXnuKMhDP9s5vKfuis4Ugul3lEZ5jX0m4_P-gaBtSlv2yX5Bg2pdzQ
link.rule.ids 230,309,786,891,25594,76906
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT4NAEJ401VhvWjXW5x4MiQeilEfh0BhYFkHLQgg1vRGgNOmlNhbj33eW0OpFb5vZZF_ZmW--3Z1ZgLvHRZGr6GjISmFWsoYYIhemWcpDS1cRr8W2EvHOITf8qfYy02cdWG5jYZo8oV9NckTUqBL1vW7s9frnEMtt3lZuHoolit6fvHTsSi07RnRTFVVynTGLIzeiEqVYkniCxlpHomHYSJT2RiI5r_Cc3hwRlLL-jSjeEezH2NiqPoZOtepDj24_XuvDQdjed2OxVb3NCdyHLPUjl0QeiZPIndKAPxObJIxGoRNwm6dCnrKAnwLxWEp9GfvMdvPLWLwbnXoGXaT91TmQEWpanlfm3EKXJUcat0CqZ5ZaUSqlZZjDAQz-bObin7pb6PlpOMkmAX-9hEOxaOJNlaJeQbf--KyuEWTr4qZZnm_Ijnoh
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=METHOD+OF+PRODUCING+A+RECOMBINANT+PROTEIN&rft.inventor=LEWIS%2C+Alan+Peter&rft.inventor=LEWIS%2C+William+John+Kenneth&rft.inventor=HOARE%2C+Michael&rft.inventor=MCINALLY%2C+Adam+Daniel&rft.inventor=UDEN%2C+Mark&rft.inventor=FINKA%2C+Gary+Brian&rft.inventor=VOULGARIS%2C+Ioannis&rft.inventor=EMMINS%2C+Robyn+Alexandra&rft.date=2019-03-13&rft.externalDBID=A1&rft.externalDocID=EP3452496A1