FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY

A series of fused pentacyclic imidazole derivatives, being potent modulators of f benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disord...

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Main Authors KEYAERTS, Jean, HEER, Jag Paul
Format Patent
LanguageEnglish
French
German
Published 06.02.2019
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Abstract A series of fused pentacyclic imidazole derivatives, being potent modulators of f benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 5,7,8,15-tetrahydro-6H-8,15- methanobenzimidazo[1,2-b][2,5]benzodiazocin-6-one derivatives and analogs thereof.
AbstractList A series of fused pentacyclic imidazole derivatives, being potent modulators of f benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 5,7,8,15-tetrahydro-6H-8,15- methanobenzimidazo[1,2-b][2,5]benzodiazocin-6-one derivatives and analogs thereof.
Author KEYAERTS, Jean
HEER, Jag Paul
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DocumentTitleAlternate DÉRIVÉS D'IMIDAZOLE PENTACYCLIQUES CONDENSÉS UTILISÉS EN TANT QUE MODULATEURS DE L'ACTIVITÉ DU TNF
KONDENSIERTE PENTACYCLISCHE DERIVATE ALS MODULATOREN DER TNF-AKTIVITÄT
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Snippet A series of fused pentacyclic imidazole derivatives, being potent modulators of f benefit in the treatment and/or prevention of various human ailments,...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY
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