USE AND MONITORING OF INHALED NITRIC OXIDE WITH LEFT VENTRICULAR ASSIST DEVICES

• Main Authors: FLANAGAN, Craig, GREENE, Douglas, Alan, POTENZIANO, Jim
• Format: Patent
• Language: English; French; German
• Published: 19.12.2018
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DIAGNOSIS; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SURGERY

A system for determining whether a patient with pulmonary hypertension will resolve the pulmonary hypertension with continued use of a left ventricular assist device (LVAD), comprises:a means for measuring one or more pulmonary hemodynamic parameters of a patient with an LVAD to obtain a first pulmonary hemodynamic value;a nitric oxide delivery device configured for, after obtaining the first pulmonary hemodynamic value, administering inhaled nitric oxide to the patient with the LVAD; anda means for measuring one or more pulmonary hemodynamic parameters of the patient during or after the inhaled nitric oxide administration to obtain a second pulmonary hemodynamic value,wherein the nitric oxide delivery device is configured for adjusting the inhaled nitric oxide based on a comparison of the second pulmonary hemodynamic value to a predetermined range, andwherein the pulmonary hemodynamic parameter is selected from left atrial pressure and pulmonary capillary wedge pressure;wherein an increase in left atrial pressure and/or pulmonary capillary wedge pressure from the first pulmonary hemodynamic value to the second pulmonary hemodynamic value of less than 5 mm Hg is indicative of improvement.