MEANS AND METHODS FOR SELECTING TRANSFORMED CELLS

The present invention relates to a nucleic acid molecule at least one nucleotide sequence encoding a selection marker indicating homologous recombination in a eukaryotic cell and at least one nucleotide sequence encoding a selection marker indicating heterologous recombination in said eukaryotic cel...

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Bibliographic Details
Main Authors FUENZALIDA, Jonathan Arias, SCHWAMBORN, Jens, JARAZO, Javier, QING, Xiaobing
Format Patent
LanguageEnglish
French
German
Published 05.12.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a nucleic acid molecule at least one nucleotide sequence encoding a selection marker indicating homologous recombination in a eukaryotic cell and at least one nucleotide sequence encoding a selection marker indicating heterologous recombination in said eukaryotic cell. The present invention also relates to a composition of matter comprising at least two nucleic acid molecules of the invention. The present invention further relates to in vitro methods for enriching or producing eukaryotic cells which are modified by homologous recombination.
Bibliography:Application Number: EP20170702836