RADIOLABELLED MGLUR2/3 PET LIGANDS

• Main Authors: BORMANS, Guy, Maurits, R, VAN GOOL, Michiel, Luc, Maria, VERBEEK, Joost, ANDRÉS-GIL, José, Ignacio
• Format: Patent
• Language: English; French; German
• Published: 24.10.2018
• Subjects: APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to novel, radiolabeled mGluR2/3 ligands, selective versus other mGlu receptors which are useful for imaging and quantifying the metabotropic glutamate receptor mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositio...