ANTI-AP2 ANTIBODIES AND ANTIGEN BINDING AGENTS TO TREAT METABOLIC DISORDERS

• Main Authors: ADAMS, Ralph, ENGIN, Feyza, DOYLE, Carl, Brendan, HERVÉ, Karine, Jeannine Madeleine, HOTAMISLIGIL, Gökhan, S, WIDENMAIER, Scott, B, WALES, Shauna, Mhairi, ROBERTS, Elisabeth, Helen, MOORE, Adrian, Richard, BURAK, Mehmet, F, TYSON, Kerry, Louise
• Format: Patent
• Language: English; French; German
• Published: 07.03.2018
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

This invention is in the area of improved anti-aP2 antibodies and antigen binding agents, and compositions thereof, which target the lipid chaperone aP2/FABP4 (referred to as "aP2") for use in treating disorders such as diabetes, obesity, cardiovascular disease, fatty liver disease, and/or...