METHODS FOR TREATING PROTEINOPATHIES
This disclosure relates to a method of treating a proteinopathy in a subject, the method comprising administering to the subject an effective amount of a quinuclidine compound. The disclosure also relates to a method of reducing, reversing or preventing the accumulation of protein aggregates in tiss...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French German |
| Published |
20.12.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | This disclosure relates to a method of treating a proteinopathy in a subject, the method comprising administering to the subject an effective amount of a quinuclidine compound. The disclosure also relates to a method of reducing, reversing or preventing the accumulation of protein aggregates in tissue of a subject diagnosed as having a proteinopathy, or being at risk of developing a proteinopathy, the method comprising administering to the subject an effective amount of a quinuclidine compound. Also disclosed is a pharmaceutical composition comprising a quinuclidine compound for use in said methods. The proteinopathy may be a synucleinopathy or a tauopathy, such as Parkinson's disease, Alzheimer's disease or dementia with Lewy bodies. |
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| AbstractList | This disclosure relates to a method of treating a proteinopathy in a subject, the method comprising administering to the subject an effective amount of a quinuclidine compound. The disclosure also relates to a method of reducing, reversing or preventing the accumulation of protein aggregates in tissue of a subject diagnosed as having a proteinopathy, or being at risk of developing a proteinopathy, the method comprising administering to the subject an effective amount of a quinuclidine compound. Also disclosed is a pharmaceutical composition comprising a quinuclidine compound for use in said methods. The proteinopathy may be a synucleinopathy or a tauopathy, such as Parkinson's disease, Alzheimer's disease or dementia with Lewy bodies. |
| Author | CHENG, Seng, H SHIHABUDDIN, Lamya SARDI, Sergio, Pablo |
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| DocumentTitleAlternate | PROCÉDÉS DE TRAITEMENT DE PROTÉINOPATHIES VERFAHREN ZUR BEHANDLUNG VON PROTEINOPATHIEN |
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| Notes | Application Number: EP20160711088 |
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| RelatedCompanies | Genzyme Corporation |
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| Snippet | This disclosure relates to a method of treating a proteinopathy in a subject, the method comprising administering to the subject an effective amount of a... |
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| Title | METHODS FOR TREATING PROTEINOPATHIES |
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