COMPLEXES AND SALTS OF DIHYDROPYRIMIDINE DERIVATIVES AND THEIR APPLICATION IN PHARMACEUTICALS

• Main Authors: LIU, Xinchang, HUANGFU, Desheng, LIANG, Jinsheng, REN, Qingyun, ZHANG, Yingjun, YAN, Guanghua, ZOU, Zhifu, CHEN, Liang, WU, Chenliang, GOLDMANN, Siegfried
• Format: Patent
• Language: English; French; German
• Published: 13.12.2017
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

This invention relates to L-tartaric acid complexes, acid addition salts, base addition salts of the compound named (S)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl) methyl) morpholine-3-carboxylic acid or tautomer thereof and pharmaceutical comp...