FACTOR XIA INHIBITORS
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibi...
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Format | Patent |
Language | English French German |
Published |
27.06.2018
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Abstract | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein. |
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AbstractList | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein. |
Author | EDMONDSON, Scott, D NEELAMKAVIL, Santhosh, F SUN, Wanying LIU, Weiguo BROCKUNIER, Linda, L MERTZ, Eric MONINGKA, Remond HRUZA, Alan GAO, Ying-Duo SO, Sung-Sau ALI, Amjad |
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DocumentTitleAlternate | INHIBITEURS DU FACTOR XIA FAKTOR-XIA-HEMMER |
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RelatedCompanies | Merck Sharp & Dohme Corp |
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Snippet | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said... |
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Title | FACTOR XIA INHIBITORS |
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