FACTOR XIa INHIBITORS

• Main Authors: ALI, Amjad, SO, Sung-Sau, GAO, Ying-Duo, HRUZA, Alan, W, HE, Jiafang, EDMONDSON, Scott D, MERTZ, Eric, GUO, Zhuyan
• Format: Patent
• Language: English; French; German
• Published: 03.01.2018
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides a compound of Formula (I) (Formula(I)) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Fact...