N-(3-(QUINOXALIN-6-YLAMINO)PHENYL)ALKANE-SULFONAMIDE DERIVATIVES AS B-RAF KINASE INHIBITORS FOR TREATING CANCER

wherein L is NR8 or O; R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases. Methods of using compounds of formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagno...

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Main Authors YEN, Shih-Chieh, PENG, Shao-zheng, KUO, Mann-Yan, LIAO, Chu-bin, LIN, Nan-horng
Format Patent
LanguageEnglish
French
German
Published 20.10.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract wherein L is NR8 or O; R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases. Methods of using compounds of formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed
AbstractList wherein L is NR8 or O; R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases. Methods of using compounds of formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed
Author YEN, Shih-Chieh
LIAO, Chu-bin
KUO, Mann-Yan
LIN, Nan-horng
PENG, Shao-zheng
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DocumentTitleAlternate N-(3-(QUINOXALIN-6-YLAMINO)PHENYL)ALKAN-SULFONAMID-DERIVATE ALS B-RAF KINASE INHIBITOREN ZUR BEHANDLUNG VON KREBS
DÉRIVÉS SULFONAMIDES DE N-(3-(QUINOXALIN-6-YLAMINO)PHÉNYL)ALKANE EN TANT QU'INHIBITEURS DE LA KINASE B-RAF POUR LE TRAITEMENT DU CANCER
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Development Center for Biotechnology
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Snippet wherein L is NR8 or O; R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases. Methods of...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title N-(3-(QUINOXALIN-6-YLAMINO)PHENYL)ALKANE-SULFONAMIDE DERIVATIVES AS B-RAF KINASE INHIBITORS FOR TREATING CANCER
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