SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS

• Main Authors: GAUTHIER, SIMON J, SUN, JIANYU, DOUGLAS, AMY FRANCES, CHOWDHURY, SULTAN, CHAKKA, NAGASREE, LANGILLE, JONATHAN, CADIEUX, JEAN-JACQUES, WOOD, MARK, FRASER, LAUREN, SVIRIDOV, SERGUEI, JIA, QI, LIU, SHIFENG, CIKOJEVIC, ZORAN, CHAFEEV, MIKHAIL, FU, JIAN-MIN, HSIEH, TOM, SUN, SHAOYI, ZENOVA, ALLA
• Format: Patent
• Language: English; French; German
• Published: 11.11.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

This invention is directed to spiro-oxindole compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.