FUSION POLYPEPTIDES AND USES THEREOF

The present invention provides Relaxin fusion polypeptides with extended half-life. Thereby, the half-life extending parts are either the Fc moiety of the human IgG2 or of the human IgG4. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors c...

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Main Authors SCHEERER, Nina Alexandra, JÖRISSEN, Hannah, LEINEWEBER, Kirsten, WILMEN, Andreas
Format Patent
LanguageEnglish
French
German
Published 04.11.2015
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Abstract The present invention provides Relaxin fusion polypeptides with extended half-life. Thereby, the half-life extending parts are either the Fc moiety of the human IgG2 or of the human IgG4. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, pharmaceutical compositions and medical use of such fusion polypeptides.
AbstractList The present invention provides Relaxin fusion polypeptides with extended half-life. Thereby, the half-life extending parts are either the Fc moiety of the human IgG2 or of the human IgG4. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, pharmaceutical compositions and medical use of such fusion polypeptides.
Author SCHEERER, Nina Alexandra
JÖRISSEN, Hannah
LEINEWEBER, Kirsten
WILMEN, Andreas
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DocumentTitleAlternate FUSIONSPOLYPEPTIDE UND VERWENDUNGEN DAVON
POLYPEPTIDES DE FUSION ET LEURS UTILISATIONS
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Snippet The present invention provides Relaxin fusion polypeptides with extended half-life. Thereby, the half-life extending parts are either the Fc moiety of the...
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METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Title FUSION POLYPEPTIDES AND USES THEREOF
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