TRICHODERMA REESEI GLUCOAMYLASE VARIANTS RESISTANT TO OXIDATION-RELATED ACTIVITY LOSS AND THE USE THEREOF

• Main Authors: GRAYCAR, THOMAS P, WONG, DAVID L, CHOW, SU YIN MARIA, VROEMEN, CASPER, HUITINK, JACQUELYN A
• Format: Patent
• Language: English; French; German
• Published: 24.06.2015
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Embodiments of the present disclosure relate to Trichoderma reesei glucoamylase (TrGA) variants having improved properties (e.g., improved thermostability, improved specific activity, and/or resistant to oxidation-related activity loss). Also provided are compositions comprising variant glucoamylase...