HETEROARYLS AND USES THEREOF

This invention provides compounds of formula IB: wherein HY, R1, R2, R3, R15, G5, G6, G7, G8, and G9 are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

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Main Authors LI, GANG, HU, YONGBO, SINTCHAK, MICHAEL, D, CHAU, RYAN, W, VOS, TRICIA, J, CULLIS, COURTNEY, A, DUFFEY, MATTHEW, O, GIPSON, KRISTA, E, STROUD, STEVEN, G
Format Patent
LanguageEnglish
French
German
Published 01.07.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract This invention provides compounds of formula IB: wherein HY, R1, R2, R3, R15, G5, G6, G7, G8, and G9 are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
AbstractList This invention provides compounds of formula IB: wherein HY, R1, R2, R3, R15, G5, G6, G7, G8, and G9 are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
Author VOS, TRICIA, J
GIPSON, KRISTA, E
HU, YONGBO
CHAU, RYAN, W
CULLIS, COURTNEY, A
DUFFEY, MATTHEW, O
LI, GANG
SINTCHAK, MICHAEL, D
STROUD, STEVEN, G
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– fullname: VOS, TRICIA, J
– fullname: CULLIS, COURTNEY, A
– fullname: DUFFEY, MATTHEW, O
– fullname: GIPSON, KRISTA, E
– fullname: STROUD, STEVEN, G
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DocumentTitleAlternate HÉTÉROARYLES ET UTILISATIONS DE CEUX-CI
HETEROARYLE UND VERWENDUNGEN DAVON
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Snippet This invention provides compounds of formula IB: wherein HY, R1, R2, R3, R15, G5, G6, G7, G8, and G9 are as described in the specification. The compounds are...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title HETEROARYLS AND USES THEREOF
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