CRYSTALLINE FORM OF CABAZITAXEL AND PROCESS FOR PREPARING THE SAME

The present invention relates to a novel crystalline ethyl acetate solvate form of cabazitaxel or 4α-acetoxy-2α-benzoyloxy-5 ,20-epoxy-1 -hydroxy-7 ,10 -dimethoxy-9-oxo-11-taxen-13α-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate and process for preparing the same.

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Bibliographic Details
Main Authors ZASKE, Lionel, DIDIER, Eric, TREMAUDEUX, Nicolas
Format Patent
LanguageEnglish
French
German
Published 23.01.2019
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Abstract The present invention relates to a novel crystalline ethyl acetate solvate form of cabazitaxel or 4α-acetoxy-2α-benzoyloxy-5 ,20-epoxy-1 -hydroxy-7 ,10 -dimethoxy-9-oxo-11-taxen-13α-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate and process for preparing the same.
AbstractList The present invention relates to a novel crystalline ethyl acetate solvate form of cabazitaxel or 4α-acetoxy-2α-benzoyloxy-5 ,20-epoxy-1 -hydroxy-7 ,10 -dimethoxy-9-oxo-11-taxen-13α-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate and process for preparing the same.
Author TREMAUDEUX, Nicolas
ZASKE, Lionel
DIDIER, Eric
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DocumentTitleAlternate KRISTALLINE FORM VON CABAZITAXEL UND HERSTELLUNGSVERFAHREN DAFÜR
FORME CRISTALLINE DU CABAZITAXEL ET SON PROCÉDÉ DE PRÉPARATION
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Snippet The present invention relates to a novel crystalline ethyl acetate solvate form of cabazitaxel or 4α-acetoxy-2α-benzoyloxy-5 ,20-epoxy-1 -hydroxy-7 ,10...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title CRYSTALLINE FORM OF CABAZITAXEL AND PROCESS FOR PREPARING THE SAME
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