GUANIDINOBENZOIC ACID COMPOUND
[Problem] Provided is a compound which is useful as an agent for preventing and/or treating renal diseases. [Means for Solution] The present inventors have conducted extensive studies on compounds having a trypsin inhibitory action, and as a result, they have found that a guanidinobenzoic acid compo...
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| Main Authors | , , , , , , , |
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| Format | Patent |
| Language | English French German |
| Published |
25.02.2015
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| Subjects | |
| Online Access | Get full text |
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| Abstract | [Problem] Provided is a compound which is useful as an agent for preventing and/or treating renal diseases. [Means for Solution] The present inventors have conducted extensive studies on compounds having a trypsin inhibitory action, and as a result, they have found that a guanidinobenzoic acid compound has a trypsin inhibitory action, thereby completing the present invention. The guanidinobenzoic acid compound of the present invention can be used as an agent for preventing and/or treating renal disease as an agent which will substitute low-protein diet therapy, and an agent for preventing and/or treating trypsin-related diseases, for example, pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like. |
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| AbstractList | [Problem] Provided is a compound which is useful as an agent for preventing and/or treating renal diseases. [Means for Solution] The present inventors have conducted extensive studies on compounds having a trypsin inhibitory action, and as a result, they have found that a guanidinobenzoic acid compound has a trypsin inhibitory action, thereby completing the present invention. The guanidinobenzoic acid compound of the present invention can be used as an agent for preventing and/or treating renal disease as an agent which will substitute low-protein diet therapy, and an agent for preventing and/or treating trypsin-related diseases, for example, pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like. |
| Author | YAMAKI, SUSUMU FUJIYASU, JIRO OHNE, KAZUHIKO MATSUURA, KEISUKE IMAIZUMI, TOMOYOSHI SATOU, TOMOHKI HONDO, TAKESHI SASAMURA, SATOSHI |
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| DocumentTitleAlternate | COMPOSÉ D'ACIDE GUANIDINOBENZOÏQUE GUANIDINOBENZOESÄUREVERBINDUNG |
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| Notes | Application Number: EP20120831685 |
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| RelatedCompanies | ASTELLAS PHARMA INC |
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| Snippet | [Problem] Provided is a compound which is useful as an agent for preventing and/or treating renal diseases. [Means for Solution] The present inventors have... |
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| SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | GUANIDINOBENZOIC ACID COMPOUND |
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