COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

• Main Authors: LOREN, JON, NGUYEN, BAO, LI, XIAOLIN, LIU, XIAODONG, PETRASSI, HANK MICHAEL JAMES, NABAKKA, JULIET, YEH, VINCE, MOLTENI, VALENTINA
• Format: Patent
• Language: English; French; German
• Published: 09.07.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some e...