COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS
The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some e...
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Format | Patent |
Language | English French German |
Published |
09.07.2014
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Abstract | The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFR ) kinases. |
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AbstractList | The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFR ) kinases. |
Author | LIU, XIAODONG LOREN, JON NGUYEN, BAO YEH, VINCE PETRASSI, HANK MICHAEL JAMES MOLTENI, VALENTINA LI, XIAOLIN NABAKKA, JULIET |
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DocumentTitleAlternate | VERBINDUNGEN UND ZUSAMMENSETZUNGEN ALS C-KIT-KINASEHEMMER COMPOSÉS ET COMPOSITIONS POUVANT ÊTRE UTILISÉS EN TANT QU'INHIBITEURS DE LA KINASE C-KIT |
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Snippet | The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as... |
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Title | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS |
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