Modified parvovirus useful for gene silencing

Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvov...

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Main Authors MARCHINI, ANTONIO, LEUCHS, BARBARA, ILLARIONOVA, ANNA, ROMMELAERE, JEAN
Format Patent
LanguageEnglish
French
German
Published 22.10.2014
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Abstract Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvovirus.
AbstractList Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvovirus.
Author ROMMELAERE, JEAN
MARCHINI, ANTONIO
ILLARIONOVA, ANNA
LEUCHS, BARBARA
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DocumentTitleAlternate Parvovirus modifié utile pour le silençage génique
Modifizierter Parvovirus zur Genausschaltung
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Snippet Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an...
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SourceType Open Access Repository
SubjectTerms AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
CARE OF BIRDS, FISHES, INSECTS
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NEW BREEDS OF ANIMALS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
SPIRITS
TRAPPING
VINEGAR
WINE
Title Modified parvovirus useful for gene silencing
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