SINGLE CHAIN RELAXIN POLYPEPTIDES

• Main Authors: LAWRENCE, ANDREW, J, HAUGAARD-KEDSTROM, LINDA MARIA, HOSSAIN, MOHAMMED, AKHTER, BATHGATE, ROSS, ALEXANDER, DAVID, WADE, JOHN, DESMOND, GUNDLACH, ANDREW, LAWRENCE, ROSENGREN, KARL, JOHAN
• Format: Patent
• Language: English; French; German
• Published: 26.10.2016
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are anta...