SINGLE CHAIN RELAXIN POLYPEPTIDES

The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are anta...

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Main Authors LAWRENCE, ANDREW, J, HAUGAARD-KEDSTROM, LINDA MARIA, HOSSAIN, MOHAMMED, AKHTER, BATHGATE, ROSS, ALEXANDER, DAVID, WADE, JOHN, DESMOND, GUNDLACH, ANDREW, LAWRENCE, ROSENGREN, KARL, JOHAN
Format Patent
LanguageEnglish
French
German
Published 26.10.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.
AbstractList The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.
Author ROSENGREN, KARL, JOHAN
LAWRENCE, ANDREW, J
WADE, JOHN, DESMOND
BATHGATE, ROSS, ALEXANDER, DAVID
GUNDLACH, ANDREW, LAWRENCE
HAUGAARD-KEDSTROM, LINDA MARIA
HOSSAIN, MOHAMMED, AKHTER
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– fullname: GUNDLACH, ANDREW, LAWRENCE
– fullname: ROSENGREN, KARL, JOHAN
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DocumentTitleAlternate POLYPEPTIDES DE RELAXINE MONOCATÉNAIRES
EINKETTIGE RELAXIN-POLYPEPTIDE
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RelatedCompanies THE UNIVERSITY OF QUEENSLAND
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Snippet The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title SINGLE CHAIN RELAXIN POLYPEPTIDES
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