SULFONAMIDE COMPOUNDS USEFUL AS CYP17 INHIBITORS

Disclosed are sulfonamide compounds of Formula (I): or stereoisomers, N-oxides, prodrugs, or pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, R4 and R5 are defined herein. Also disclosed are methods of using such compounds in the treatment of conditions related to CYP17 enzyme,...

Full description

Saved in:
Bibliographic Details
Main Authors AUSTIN, JOEL FRANCIS, SAULNIER, MARK GEORGE, BALOG, JAMES AARON, SHARMA, LISA S, HUANG, AUDRIS, VELAPARTHI, UPENDER, DARNE, CHETAN PADMAKAR
Format Patent
LanguageEnglish
French
German
Published 31.08.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

Abstract Disclosed are sulfonamide compounds of Formula (I): or stereoisomers, N-oxides, prodrugs, or pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, R4 and R5 are defined herein. Also disclosed are methods of using such compounds in the treatment of conditions related to CYP17 enzyme, such as cancer, and pharmaceutical compositions comprising such compounds.
AbstractList Disclosed are sulfonamide compounds of Formula (I): or stereoisomers, N-oxides, prodrugs, or pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, R4 and R5 are defined herein. Also disclosed are methods of using such compounds in the treatment of conditions related to CYP17 enzyme, such as cancer, and pharmaceutical compositions comprising such compounds.
Author AUSTIN, JOEL FRANCIS
SHARMA, LISA S
BALOG, JAMES AARON
SAULNIER, MARK GEORGE
DARNE, CHETAN PADMAKAR
HUANG, AUDRIS
VELAPARTHI, UPENDER
Author_xml – fullname: AUSTIN, JOEL FRANCIS
– fullname: SAULNIER, MARK GEORGE
– fullname: BALOG, JAMES AARON
– fullname: SHARMA, LISA S
– fullname: HUANG, AUDRIS
– fullname: VELAPARTHI, UPENDER
– fullname: DARNE, CHETAN PADMAKAR
BookMark eNrjYmDJy89L5WQwCA71cfP3c_T1dHFVcPb3DfAP9XMJVggNdnUL9VFwDFZwjgwwNFfw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BRqaWFiYWhk6GxkQoAQDnpSfP
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate SULFONAMIDVERBINDUNGEN ALS CYP17-HEMMER
COMPOSÉS DE SULFONAMIDE UTILES EN TANT QU'INHIBITEURS DE CYP17
ExternalDocumentID EP2598481B1
GroupedDBID EVB
ID FETCH-epo_espacenet_EP2598481B13
IEDL.DBID EVB
IngestDate Fri Jul 19 15:02:51 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
German
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_EP2598481B13
Notes Application Number: EP20110741378
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160831&DB=EPODOC&CC=EP&NR=2598481B1
ParticipantIDs epo_espacenet_EP2598481B1
PublicationCentury 2000
PublicationDate 20160831
PublicationDateYYYYMMDD 2016-08-31
PublicationDate_xml – month: 08
  year: 2016
  text: 20160831
  day: 31
PublicationDecade 2010
PublicationYear 2016
RelatedCompanies BRISTOL-MYERS SQUIBB COMPANY
RelatedCompanies_xml – name: BRISTOL-MYERS SQUIBB COMPANY
Score 3.0528257
Snippet Disclosed are sulfonamide compounds of Formula (I): or stereoisomers, N-oxides, prodrugs, or pharmaceutically acceptable salts thereof, wherein ring A, R1, R2,...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title SULFONAMIDE COMPOUNDS USEFUL AS CYP17 INHIBITORS
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160831&DB=EPODOC&locale=&CC=EP&NR=2598481B1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT8MwDLamgYAbDBDjpRxQbxV9pHscJrSmrVq0NtW6onGaSJtKu2wTK-Lv45ZucIGblUhOYumLH4ltgIeCWpIOTFMtxEBTqSFNFT1bTTWGop-jeYEqsUoUDqOen9LnuTVvwXKXC1PXCf2siyMiojLEe1nf15ufIJZT_63cPoolDq2fvNnIURrvWO9VjbMUxx65MXc4UxhDSommI7Tyq8LxNjpKB2hF9yswuC92lZSy-a1RvFM4jJHZqjyDllx14JjtGq914Chs3ruRbKC3PQctSScej8Zh4LiE8TDmaeQkJE1cL52QcULYa6z3SRD5gR3M-DS5AOK5M-aruPRif8yFG-83aV5CG71_eQUELShLz4SeW4JSI5eiyIV4o6InMz0b6lkXun-yuf5n7gZOKnl9h0dvoV2-f8g71K-luK8l8wVFf3q5
link.rule.ids 230,309,783,888,25576,76876
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT4NAEJ401VhvWjXW5x4MN2IpC7SHxpQFAsorBUw9NS5sk15qYzH-fQek1YveJrvJ7O4k385jd2YA7hZUE3SoqvKCD_syHQhVRs-2Lw9G3CjQvECVWCUKB6HuZvRxps1asNzmwtR1Qj_r4oiIqBzxXtb39foniGXVfys393yJQ28PTjq2pMY7VvSqcZZkmWM7jqyISYwhJYXTMVr5VeF4Ex2lPbSwjQoM9rNZJaWsf2sU5wj2Y2S2Ko-hJVZd6LBt47UuHATNezeSDfQ2J9BPMt-JwkngWTZhURBHWWglJEtsJ_PJJCHsJVYM4oWuZ3ppNE1OgTh2ylwZl57vjjm3490m1TNoo_cvzoGgBaUpOVcKjVM6KARfFJy_Uq6LXMlHSt6D3p9sLv6Zu4WOmwb-3PfCp0s4rGT3HSq9gnb5_iGuUdeW_KaW0hcxwX2s
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=SULFONAMIDE+COMPOUNDS+USEFUL+AS+CYP17+INHIBITORS&rft.inventor=AUSTIN%2C+JOEL+FRANCIS&rft.inventor=SAULNIER%2C+MARK+GEORGE&rft.inventor=BALOG%2C+JAMES+AARON&rft.inventor=SHARMA%2C+LISA+S&rft.inventor=HUANG%2C+AUDRIS&rft.inventor=VELAPARTHI%2C+UPENDER&rft.inventor=DARNE%2C+CHETAN+PADMAKAR&rft.date=2016-08-31&rft.externalDBID=B1&rft.externalDocID=EP2598481B1