N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 inhibitors are potentially useful in the treatm...
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Format | Patent |
Language | English French German |
Published |
21.01.2015
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Abstract | The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain. |
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AbstractList | The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain. |
Author | STORER, ROBERT IAN MARRON, BRIAN EDWARD ZHOU, SHULAN SWAIN, NIGEL ALAN RAWSON, DAVID JAMES MARKWORTH, CHRISTOPHER JOHN WEST, CHRISTOPHER WILLIAM |
Author_xml | – fullname: STORER, ROBERT IAN – fullname: ZHOU, SHULAN – fullname: MARRON, BRIAN EDWARD – fullname: WEST, CHRISTOPHER WILLIAM – fullname: RAWSON, DAVID JAMES – fullname: SWAIN, NIGEL ALAN – fullname: MARKWORTH, CHRISTOPHER JOHN |
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DocumentTitleAlternate | N-SULFONYLBENZAMIDE ALS INHIBITOREN VON SPANNUNGSABHÄNGIGEN NATRIUMKANÄLEN N-SULFONYLBENZAMIDES COMME INHIBITEURS DES CANAUX SODIQUES VOLTAGE-DÉPENDANT |
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RelatedCompanies | PFIZER LIMITED ICAGEN, INC |
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Snippet | The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing... |
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SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS |
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