N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS

The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 inhibitors are potentially useful in the treatm...

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Main Authors STORER, ROBERT IAN, ZHOU, SHULAN, MARRON, BRIAN EDWARD, WEST, CHRISTOPHER WILLIAM, RAWSON, DAVID JAMES, SWAIN, NIGEL ALAN, MARKWORTH, CHRISTOPHER JOHN
Format Patent
LanguageEnglish
French
German
Published 21.01.2015
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Abstract The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
AbstractList The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
Author STORER, ROBERT IAN
MARRON, BRIAN EDWARD
ZHOU, SHULAN
SWAIN, NIGEL ALAN
RAWSON, DAVID JAMES
MARKWORTH, CHRISTOPHER JOHN
WEST, CHRISTOPHER WILLIAM
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– fullname: SWAIN, NIGEL ALAN
– fullname: MARKWORTH, CHRISTOPHER JOHN
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DocumentTitleAlternate N-SULFONYLBENZAMIDE ALS INHIBITOREN VON SPANNUNGSABHÄNGIGEN NATRIUMKANÄLEN
N-SULFONYLBENZAMIDES COMME INHIBITEURS DES CANAUX SODIQUES VOLTAGE-DÉPENDANT
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ICAGEN, INC
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Snippet The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
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