Arminothiazole derivatives as human stearoyl-coa desaturase inhibitors

Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where V, W, R 1 , R 2 , R 3 and R 4 are defined herein. Pharmaceutical compositions comprising th...

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Bibliographic Details
Main Authors HOU, DUANJIE, VISHNUMURTHY, KODUMURU, RAINA, VANDNA, ZHANG, ZAIHUI, FU, JIAN-MIN, RAJENDER, KAMBOJ, PROKOVSKAIA, NATALIA, SUN, SHAOYI, SVIRIDOV, SERGUEI
Format Patent
LanguageEnglish
French
German
Published 02.01.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where V, W, R 1 , R 2 , R 3 and R 4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Bibliography:Application Number: EP20120005821