PARTICLE COMPOSITION AND MEDICINAL COMPOSITION COMPRISING SAME
The present invention provides a particulate composition containing: block copolymer units being arranged radially with hydrophobic polymer-chain segments radially inside and hydrophilic polymer-chain segments radially outside; and a charged lipid which carries a charge opposite to the charge of a d...
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Main Authors | , |
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Format | Patent |
Language | English French German |
Published |
11.07.2012
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Subjects | |
Online Access | Get full text |
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Abstract | The present invention provides a particulate composition containing: block copolymer units being arranged radially with hydrophobic polymer-chain segments radially inside and hydrophilic polymer-chain segments radially outside; and a charged lipid which carries a charge opposite to the charge of a drug to be encapsulated, the charged lipid being attracted to the hydrophobic polymer-chain segment. In this particulate composition, the drug is retained within the particle via electrostatic binding with the charged lipid, whereby the outer surface of the particle is prevented from being charged to attract a substance which has a charge opposite to that of the charged lipid. |
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AbstractList | The present invention provides a particulate composition containing: block copolymer units being arranged radially with hydrophobic polymer-chain segments radially inside and hydrophilic polymer-chain segments radially outside; and a charged lipid which carries a charge opposite to the charge of a drug to be encapsulated, the charged lipid being attracted to the hydrophobic polymer-chain segment. In this particulate composition, the drug is retained within the particle via electrostatic binding with the charged lipid, whereby the outer surface of the particle is prevented from being charged to attract a substance which has a charge opposite to that of the charged lipid. |
Author | KATO, YASUKI ISHII, ATSUSHI |
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Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | COMPOSITION PARTICULAIRE ET COMPOSITION MÉDICAMENTEUSE COMPRENANT CELLE-CI PARTIKELZUSAMMENSETZUNG UND MEDIZINISCHE VORRICHTUNG DAMIT |
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RelatedCompanies | NANOCARRIER CO., LTD |
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Snippet | The present invention provides a particulate composition containing: block copolymer units being arranged radially with hydrophobic polymer-chain segments... |
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SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
Title | PARTICLE COMPOSITION AND MEDICINAL COMPOSITION COMPRISING SAME |
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