USEFUL PHARMACEUTICAL SALTS OF 7-[(3R, 4R)-3-HYDROXY-4-HYDROXYMETHYL-PYRROLIDIN-1-YLMETHYL]-3,5-DIHYDRO-PYRROLO[3,2-D]PYRIMIDIN-4-ONE

• Main Authors: LANG, JOHN, F, BARTLEY, GARY, CLEARY, THOMAS
• Format: Patent
• Language: English; French; German
• Published: 15.08.2012
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The present disclosure provides novel hemi- and mono-salts of 7-[(3R,4R)-3-Hydroxy-4-hydroxymethyl-pyrrolidin-1-ylmethyl]-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one (Compound 1) with various organic and inorganic acids. In one embodiment, the organic acid is a C4 organic diacids. The present disclosu...