Optimized antibodies that target CD19
The present disclosure describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an Fcg³R or alters effector function as compared to the parent antibody. Also disclosed are methods of us...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English French German |
Published |
22.03.2023
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Abstract | The present disclosure describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an Fcg³R or alters effector function as compared to the parent antibody. Also disclosed are methods of using said antibodies. |
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AbstractList | The present disclosure describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an Fcg³R or alters effector function as compared to the parent antibody. Also disclosed are methods of using said antibodies. |
Author | Pong, Erik WeiKing Richards, John O Desjarlais, John R Lazar, Gregory Alan Karki, Sher Bahadur Zhukovsky, Eugene Alexander Bernett, Matthew J Chu, Seung Yup |
Author_xml | – fullname: Bernett, Matthew J – fullname: Richards, John O – fullname: Zhukovsky, Eugene Alexander – fullname: Lazar, Gregory Alan – fullname: Karki, Sher Bahadur – fullname: Pong, Erik WeiKing – fullname: Desjarlais, John R – fullname: Chu, Seung Yup |
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DocumentTitleAlternate | Auf CD19 gerichtete optimierte Antikörper Anticorps optimisés ciblant le CD19 |
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Snippet | The present disclosure describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein... |
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Title | Optimized antibodies that target CD19 |
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