Sustained release intraocular implants comprising a beta adrenergic receptor antagonist and methods for treating ocular neuropathies

The present invention relates to a biodegradable drug delivery implant comprising: a beta adrenergic receptor antagonist, and a biodegradable polymer matrix, which comprises a poly (lactide-co-glycolide) copolymer, in the form of an intraocular implant having a dimension greater than 1 mm and that r...

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Main Authors HUANG, GLENN T, NIVAGGIOLI, THIERRY
Format Patent
LanguageEnglish
French
German
Published 11.06.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The present invention relates to a biodegradable drug delivery implant comprising: a beta adrenergic receptor antagonist, and a biodegradable polymer matrix, which comprises a poly (lactide-co-glycolide) copolymer, in the form of an intraocular implant having a dimension greater than 1 mm and that releases the beta adrenergic receptor antagonist from the implant into the eye for a time effective to reduce intraocular pressure in an eye in which the implant is placed, the time being at least about one week after the implant is placed in the eye and a method for making the same.
AbstractList The present invention relates to a biodegradable drug delivery implant comprising: a beta adrenergic receptor antagonist, and a biodegradable polymer matrix, which comprises a poly (lactide-co-glycolide) copolymer, in the form of an intraocular implant having a dimension greater than 1 mm and that releases the beta adrenergic receptor antagonist from the implant into the eye for a time effective to reduce intraocular pressure in an eye in which the implant is placed, the time being at least about one week after the implant is placed in the eye and a method for making the same.
Author NIVAGGIOLI, THIERRY
HUANG, GLENN T
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DocumentTitleAlternate Intraokulare Implantate mit verzögerter Freigabe mit einem beta-adregenischen Rezeptorantagonisten und Verfahren zur Behandlung okularer Neuropathien
Implants intra-oculaires à libération prolongée comprenant un antagoniste du récepteur bêta-adrénergique et procédés pour le traitement de neuropathies
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Snippet The present invention relates to a biodegradable drug delivery implant comprising: a beta adrenergic receptor antagonist, and a biodegradable polymer matrix,...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Sustained release intraocular implants comprising a beta adrenergic receptor antagonist and methods for treating ocular neuropathies
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