Sustained release intraocular implants comprising a beta adrenergic receptor antagonist and methods for treating ocular neuropathies

The present invention relates to a biodegradable drug delivery implant comprising: a beta adrenergic receptor antagonist, and a biodegradable polymer matrix, which comprises a poly (lactide-co-glycolide) copolymer, in the form of an intraocular implant having a dimension greater than 1 mm and that r...

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Bibliographic Details
Main Authors HUANG, GLENN T, NIVAGGIOLI, THIERRY
Format Patent
LanguageEnglish
French
German
Published 11.06.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a biodegradable drug delivery implant comprising: a beta adrenergic receptor antagonist, and a biodegradable polymer matrix, which comprises a poly (lactide-co-glycolide) copolymer, in the form of an intraocular implant having a dimension greater than 1 mm and that releases the beta adrenergic receptor antagonist from the implant into the eye for a time effective to reduce intraocular pressure in an eye in which the implant is placed, the time being at least about one week after the implant is placed in the eye and a method for making the same.
Bibliography:Application Number: EP20110161473