BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS

• Main Authors: BLUM, CHARLES, A, NG, PUI, YEE, PERNI, ROBERT, B, DISCH, JEREMY, S, VU, CHI, B
• Format: Patent
• Language: English; French; German
• Published: 04.05.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to agin...