PROCESS FOR PREPARATION OF INTERMEDIATES OF ROSIGLITAZONE, ROSIGLITAZONE AND POLYMORPHIC FORMS THEREOF
The invention relates to a polymorphic form of 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione (Formula (I)): to a process for its preparation and to the use of such compound for preparing rosiglitazone in the form of a free base or a salt thereof. The invention also r...
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| Main Author | |
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| Format | Patent |
| Language | English French German |
| Published |
04.03.2009
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention relates to a polymorphic form of 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione (Formula (I)): to a process for its preparation and to the use of such compound for preparing rosiglitazone in the form of a free base or a salt thereof. The invention also relates to a polymorphic form of rosiglitazone in the form of a free base, to a process for its preparation and to the use of such polymorph for preparing a salt of rosiglitazone. The invention also relates to a process of preparing a polymorphic form of a rosiglitazone salt. |
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| AbstractList | The invention relates to a polymorphic form of 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione (Formula (I)): to a process for its preparation and to the use of such compound for preparing rosiglitazone in the form of a free base or a salt thereof. The invention also relates to a polymorphic form of rosiglitazone in the form of a free base, to a process for its preparation and to the use of such polymorph for preparing a salt of rosiglitazone. The invention also relates to a process of preparing a polymorphic form of a rosiglitazone salt. |
| Author | LOPEZ, ERNESTO DURAN |
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| DocumentTitleAlternate | PROCÉDÉ POUR PRÉPARER DES INTERMÉDIAIRES DE LA ROSIGLITAZONE, ROSIGLITAZONE ET NOUVELLES FORMES POLYMORPHES DE CELLE-CI VERFAHREN ZUR HERSTELLUNG VON ZWISCHENPRODUKTEN VON ROSIGLITAZON, ROSIGLITAZON UND POLYMORPHE FORMEN DAVON |
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| Snippet | The invention relates to a polymorphic form of 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione (Formula (I)): to a process for... |
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| Title | PROCESS FOR PREPARATION OF INTERMEDIATES OF ROSIGLITAZONE, ROSIGLITAZONE AND POLYMORPHIC FORMS THEREOF |
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