METHOD AND DEVICE FOR THE IN VITRO ANALYSIS OF MRNA OF GENES INVOLVED IN HAEMATOLOGICAL NEOPLASIAS

Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize with genes involved in hematological neoplasias, designed so that its behaviour in the hybridization is similar, permits the evaluation of th...

Full description

Saved in:
Bibliographic Details
Main Authors POCOVI MIERAS, MIGUEL, SAENZ JIMENEZ, PILAR, ALVAREZ CABEZA, PATRICIA, GIRALDO CASTELLANO, PILAR, SIMON BUELA, LAUREANO, MARTINEZ MARTINEZ, ANTONIO
Format Patent
LanguageEnglish
French
German
Published 20.01.2010
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize with genes involved in hematological neoplasias, designed so that its behaviour in the hybridization is similar, permits the evaluation of the mRNA level in biological samples taken from subjects suspected to be suffering from hematological neoplasia and facilitating the comparison between the different samples and their grouping by similarity in the gene expression patterns, especially when the probes are disposed in the form of microarray. The application of the method of the invention to obtain and process data of gene expression differences from the device of the invention permits the identification of genes significant for distinguishing samples associated to hematological neoplasias, facilitates the diagnosis of neoplasias as CLL and permits making a prognosis of the evolution thereof.
AbstractList Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize with genes involved in hematological neoplasias, designed so that its behaviour in the hybridization is similar, permits the evaluation of the mRNA level in biological samples taken from subjects suspected to be suffering from hematological neoplasia and facilitating the comparison between the different samples and their grouping by similarity in the gene expression patterns, especially when the probes are disposed in the form of microarray. The application of the method of the invention to obtain and process data of gene expression differences from the device of the invention permits the identification of genes significant for distinguishing samples associated to hematological neoplasias, facilitates the diagnosis of neoplasias as CLL and permits making a prognosis of the evolution thereof.
Author ALVAREZ CABEZA, PATRICIA
SAENZ JIMENEZ, PILAR
POCOVI MIERAS, MIGUEL
GIRALDO CASTELLANO, PILAR
MARTINEZ MARTINEZ, ANTONIO
SIMON BUELA, LAUREANO
Author_xml – fullname: POCOVI MIERAS, MIGUEL
– fullname: SAENZ JIMENEZ, PILAR
– fullname: ALVAREZ CABEZA, PATRICIA
– fullname: GIRALDO CASTELLANO, PILAR
– fullname: SIMON BUELA, LAUREANO
– fullname: MARTINEZ MARTINEZ, ANTONIO
BookMark eNqNyk0KwjAQhuEsdOHfHeYCLsSCuByaSRNIMqUJga5KlbiStlDvjy14ABcf7-J79mIzjEPeiYejqFkCegmSkikJFDcQNYHxkExsePnQtsEEYAWu8bi2Ik9hIYltIrlajeQwsuXKlGjBE9cWg8FwFNtX_57z6deDAEWx1Oc8jV2ep_6Zh_zpqL7ci9syLK5_kC96vjTn
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate VERFAHREN UND VORRICHTUNG ZUR IN-VITRO-ANALYSE DER MRNA VON AN HÄMATOLOGISCHEN NEOPLASIEN BETEILIGTEN GENEN
PROCEDE ET DISPOSITIF D'ANALYSE IN VITRO DE L'ARNM DE GENES JOUANT UN ROLE DANS LES NEOPLASIES HEMATOLOGIQUES
ExternalDocumentID EP1947194A4
GroupedDBID EVB
ID FETCH-epo_espacenet_EP1947194A43
IEDL.DBID EVB
IngestDate Fri Jul 19 12:49:09 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
German
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_EP1947194A43
Notes Application Number: EP20060743492
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100120&DB=EPODOC&CC=EP&NR=1947194A4
ParticipantIDs epo_espacenet_EP1947194A4
PublicationCentury 2000
PublicationDate 20100120
PublicationDateYYYYMMDD 2010-01-20
PublicationDate_xml – month: 01
  year: 2010
  text: 20100120
  day: 20
PublicationDecade 2010
PublicationYear 2010
RelatedCompanies FUNDACION PARA EL ESTUDIO DE LA HEMATOLOGIA Y HEMOTERAPIA DE ARAGON (FEHHA)
RelatedCompanies_xml – name: FUNDACION PARA EL ESTUDIO DE LA HEMATOLOGIA Y HEMOTERAPIA DE ARAGON (FEHHA)
Score 2.7587986
Snippet Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize...
SourceID epo
SourceType Open Access Repository
SubjectTerms BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
Title METHOD AND DEVICE FOR THE IN VITRO ANALYSIS OF MRNA OF GENES INVOLVED IN HAEMATOLOGICAL NEOPLASIAS
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100120&DB=EPODOC&locale=&CC=EP&NR=1947194A4
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT8MgFH6Z06g3nRrnr3AwvS3KfrTbYTGs0LRmLc1am3kype1hl25xNf77Puo2veiBQHiEwEs-4AM-ALjPTVwE9xXSkmKABIUOs87ITIuOldO0N1Iqf7S0wNkPTPel_zwfzBuw2Gph6ndCP-vHERFRGeK9qsfr1c8mFq_vVq4f1AKzlk9OPObGhh3TWgtq8MlYhJJL27BtTBnBbIxc3cLA-nuwj6toS4NBJBMtSln9nlGcEzgIsbKyOoVGUbbgyN5-vNaCQ39z3o3JDfTWZ6B8EbuSExZwwkXi2YIggSOxK4gXkMSLZxJtbPoaeRGRDvFnAdOxvpsWYZFEThPBdVmXCZ_F218QSCBkOGWRx6JzII6IbbeDjX3bOeZNhLtu9S6gWS7L4hIIHeZdM7OUWQxTLWNLu4p2sxFNFbV6KlNtaP9ZzdU_tms4_j46pwitG2hW7x_FLc7IlbqrffkF9sOHpA
link.rule.ids 230,309,783,888,25576,76876
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT8IwFH5BNOJNUSP-7MHsRrQMNjgQU9Yum-5X2FzwRNZtBy6DyIz_vm8T0IsemjZ9TdO-5Gv7tf1agPtMw0VwXyItyQdIUOgw7Y60JO_qGU3UkZTZo14JnF1Ps177z7PBrAGLrRamfif0s34cERGVIt7Lerxe_Wxi8fpu5fpBLjBr-WRGY65s2DGttaAKn4xF4HPfUAwDU4o3HSNX1zGw_h7s4wpbr8Ag4kklSln9nlHMYzgIsLKiPIFGXrShZWw_XmvDobs578bkBnrrU5CuiCyfE-ZxwkVsG4IggSORJYjtkdiOpj7amPMW2iHxTeJOPVbF1d20EIvEvhMLXpW1mHBZtP0FgXjCDxwW2iw8A2KKyLC62Nj5zjFzEey6pZ5Ds1gW-QUQOsx6WqpLLR8mlYwt6UnaS0c0kVRXZSo70Pmzmst_bHfQsiLXmTu293IFR9_H6BRhdg3N8v0jv8HZuZS3tV-_AICOipc
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=METHOD+AND+DEVICE+FOR+THE+IN+VITRO+ANALYSIS+OF+MRNA+OF+GENES+INVOLVED+IN+HAEMATOLOGICAL+NEOPLASIAS&rft.inventor=POCOVI+MIERAS%2C+MIGUEL&rft.inventor=SAENZ+JIMENEZ%2C+PILAR&rft.inventor=ALVAREZ+CABEZA%2C+PATRICIA&rft.inventor=GIRALDO+CASTELLANO%2C+PILAR&rft.inventor=SIMON+BUELA%2C+LAUREANO&rft.inventor=MARTINEZ+MARTINEZ%2C+ANTONIO&rft.date=2010-01-20&rft.externalDBID=A4&rft.externalDocID=EP1947194A4