METHOD AND DEVICE FOR THE IN VITRO ANALYSIS OF MRNA OF GENES INVOLVED IN HAEMATOLOGICAL NEOPLASIAS
Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize with genes involved in hematological neoplasias, designed so that its behaviour in the hybridization is similar, permits the evaluation of th...
Saved in:
Main Authors | , , , , , |
---|---|
Format | Patent |
Language | English French German |
Published |
20.01.2010
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize with genes involved in hematological neoplasias, designed so that its behaviour in the hybridization is similar, permits the evaluation of the mRNA level in biological samples taken from subjects suspected to be suffering from hematological neoplasia and facilitating the comparison between the different samples and their grouping by similarity in the gene expression patterns, especially when the probes are disposed in the form of microarray. The application of the method of the invention to obtain and process data of gene expression differences from the device of the invention permits the identification of genes significant for distinguishing samples associated to hematological neoplasias, facilitates the diagnosis of neoplasias as CLL and permits making a prognosis of the evolution thereof. |
---|---|
AbstractList | Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize with genes involved in hematological neoplasias, designed so that its behaviour in the hybridization is similar, permits the evaluation of the mRNA level in biological samples taken from subjects suspected to be suffering from hematological neoplasia and facilitating the comparison between the different samples and their grouping by similarity in the gene expression patterns, especially when the probes are disposed in the form of microarray. The application of the method of the invention to obtain and process data of gene expression differences from the device of the invention permits the identification of genes significant for distinguishing samples associated to hematological neoplasias, facilitates the diagnosis of neoplasias as CLL and permits making a prognosis of the evolution thereof. |
Author | ALVAREZ CABEZA, PATRICIA SAENZ JIMENEZ, PILAR POCOVI MIERAS, MIGUEL GIRALDO CASTELLANO, PILAR MARTINEZ MARTINEZ, ANTONIO SIMON BUELA, LAUREANO |
Author_xml | – fullname: POCOVI MIERAS, MIGUEL – fullname: SAENZ JIMENEZ, PILAR – fullname: ALVAREZ CABEZA, PATRICIA – fullname: GIRALDO CASTELLANO, PILAR – fullname: SIMON BUELA, LAUREANO – fullname: MARTINEZ MARTINEZ, ANTONIO |
BookMark | eNqNyk0KwjAQhuEsdOHfHeYCLsSCuByaSRNIMqUJga5KlbiStlDvjy14ABcf7-J79mIzjEPeiYejqFkCegmSkikJFDcQNYHxkExsePnQtsEEYAWu8bi2Ik9hIYltIrlajeQwsuXKlGjBE9cWg8FwFNtX_57z6deDAEWx1Oc8jV2ep_6Zh_zpqL7ci9syLK5_kC96vjTn |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | VERFAHREN UND VORRICHTUNG ZUR IN-VITRO-ANALYSE DER MRNA VON AN HÄMATOLOGISCHEN NEOPLASIEN BETEILIGTEN GENEN PROCEDE ET DISPOSITIF D'ANALYSE IN VITRO DE L'ARNM DE GENES JOUANT UN ROLE DANS LES NEOPLASIES HEMATOLOGIQUES |
ExternalDocumentID | EP1947194A4 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_EP1947194A43 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 12:49:09 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French German |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_EP1947194A43 |
Notes | Application Number: EP20060743492 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100120&DB=EPODOC&CC=EP&NR=1947194A4 |
ParticipantIDs | epo_espacenet_EP1947194A4 |
PublicationCentury | 2000 |
PublicationDate | 20100120 |
PublicationDateYYYYMMDD | 2010-01-20 |
PublicationDate_xml | – month: 01 year: 2010 text: 20100120 day: 20 |
PublicationDecade | 2010 |
PublicationYear | 2010 |
RelatedCompanies | FUNDACION PARA EL ESTUDIO DE LA HEMATOLOGIA Y HEMOTERAPIA DE ARAGON (FEHHA) |
RelatedCompanies_xml | – name: FUNDACION PARA EL ESTUDIO DE LA HEMATOLOGIA Y HEMOTERAPIA DE ARAGON (FEHHA) |
Score | 2.7587986 |
Snippet | Method and device for the in vitro analysis of mRNA of genes involved in hematological neoplasias. The device, composed of probes which specifically hybridize... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
Title | METHOD AND DEVICE FOR THE IN VITRO ANALYSIS OF MRNA OF GENES INVOLVED IN HAEMATOLOGICAL NEOPLASIAS |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100120&DB=EPODOC&locale=&CC=EP&NR=1947194A4 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT8MgFH6Z06g3nRrnr3AwvS3KfrTbYTGs0LRmLc1am3kype1hl25xNf77Puo2veiBQHiEwEs-4AM-ALjPTVwE9xXSkmKABIUOs87ITIuOldO0N1Iqf7S0wNkPTPel_zwfzBuw2Gph6ndCP-vHERFRGeK9qsfr1c8mFq_vVq4f1AKzlk9OPObGhh3TWgtq8MlYhJJL27BtTBnBbIxc3cLA-nuwj6toS4NBJBMtSln9nlGcEzgIsbKyOoVGUbbgyN5-vNaCQ39z3o3JDfTWZ6B8EbuSExZwwkXi2YIggSOxK4gXkMSLZxJtbPoaeRGRDvFnAdOxvpsWYZFEThPBdVmXCZ_F218QSCBkOGWRx6JzII6IbbeDjX3bOeZNhLtu9S6gWS7L4hIIHeZdM7OUWQxTLWNLu4p2sxFNFbV6KlNtaP9ZzdU_tms4_j46pwitG2hW7x_FLc7IlbqrffkF9sOHpA |
link.rule.ids | 230,309,783,888,25576,76876 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT8IwFH5BNOJNUSP-7MHsRrQMNjgQU9Yum-5X2FzwRNZtBy6DyIz_vm8T0IsemjZ9TdO-5Gv7tf1agPtMw0VwXyItyQdIUOgw7Y60JO_qGU3UkZTZo14JnF1Ps177z7PBrAGLrRamfif0s34cERGVIt7Lerxe_Wxi8fpu5fpBLjBr-WRGY65s2DGttaAKn4xF4HPfUAwDU4o3HSNX1zGw_h7s4wpbr8Ag4kklSln9nlHMYzgIsLKiPIFGXrShZWw_XmvDobs578bkBnrrU5CuiCyfE-ZxwkVsG4IggSORJYjtkdiOpj7amPMW2iHxTeJOPVbF1d20EIvEvhMLXpW1mHBZtP0FgXjCDxwW2iw8A2KKyLC62Nj5zjFzEey6pZ5Ds1gW-QUQOsx6WqpLLR8mlYwt6UnaS0c0kVRXZSo70Pmzmst_bHfQsiLXmTu293IFR9_H6BRhdg3N8v0jv8HZuZS3tV-_AICOipc |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=METHOD+AND+DEVICE+FOR+THE+IN+VITRO+ANALYSIS+OF+MRNA+OF+GENES+INVOLVED+IN+HAEMATOLOGICAL+NEOPLASIAS&rft.inventor=POCOVI+MIERAS%2C+MIGUEL&rft.inventor=SAENZ+JIMENEZ%2C+PILAR&rft.inventor=ALVAREZ+CABEZA%2C+PATRICIA&rft.inventor=GIRALDO+CASTELLANO%2C+PILAR&rft.inventor=SIMON+BUELA%2C+LAUREANO&rft.inventor=MARTINEZ+MARTINEZ%2C+ANTONIO&rft.date=2010-01-20&rft.externalDBID=A4&rft.externalDocID=EP1947194A4 |