N-BIARYL AND N-ARYLHETEROARYL 2-SUBSTITUTED PIPERAZINE DERIVATIVES AS MODULATORS OF THE 5HT2C RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to certain N-biaryl and N-arylheteroaryl 2-substituted piperazine derivatives of Formula (Ia) that are modulators of the 5HT2C receptor. Accordingly, compounds of the present invention are useful for the treatment of 5HT2C receptor associated diseases or disorders, such...

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Main Authors ESTRADA, SCOTT A, SMITH, BRIAN M, SANTORA, VINCENT J, SCHULTZ, JEFFREY A, HAYASHI, RENA, IBARRA, JASON B
Format Patent
LanguageEnglish
French
German
Published 12.09.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention relates to certain N-biaryl and N-arylheteroaryl 2-substituted piperazine derivatives of Formula (Ia) that are modulators of the 5HT2C receptor. Accordingly, compounds of the present invention are useful for the treatment of 5HT2C receptor associated diseases or disorders, such as, obesity, Alzheimer Disease, erectile dysfunction and related disorders.
AbstractList The present invention relates to certain N-biaryl and N-arylheteroaryl 2-substituted piperazine derivatives of Formula (Ia) that are modulators of the 5HT2C receptor. Accordingly, compounds of the present invention are useful for the treatment of 5HT2C receptor associated diseases or disorders, such as, obesity, Alzheimer Disease, erectile dysfunction and related disorders.
Author SANTORA, VINCENT J
IBARRA, JASON B
HAYASHI, RENA
SMITH, BRIAN M
SCHULTZ, JEFFREY A
ESTRADA, SCOTT A
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– fullname: SANTORA, VINCENT J
– fullname: SCHULTZ, JEFFREY A
– fullname: HAYASHI, RENA
– fullname: IBARRA, JASON B
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DocumentTitleAlternate DERIVES DE PIPERAZINE 2-SUBSTITUES DE N-BIARYLE ET DE N-ARYLHETEROARYLE UTILISES COMME MODULATEURS DU RECEPTEUR 5HT2C DESTINES AU TRAITEMENT DE TROUBLES ASSOCIES AUDIT RECEPTEUR
2-SUBSTITUIERTE N-BIARYL- UND N-ARYLHETEROARYLPIPERAZINDERIVATE ALS MODULATOREN DES 5HT2C-REZEPTORS, DIE SICH FÜR DIE BEHANDLUNG VON DAMIT IN ZUSAMMENHANG STEHENDEN ERKRANKUNGEN EIGNEN
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Snippet The present invention relates to certain N-biaryl and N-arylheteroaryl 2-substituted piperazine derivatives of Formula (Ia) that are modulators of the 5HT2C...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title N-BIARYL AND N-ARYLHETEROARYL 2-SUBSTITUTED PIPERAZINE DERIVATIVES AS MODULATORS OF THE 5HT2C RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
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