ORALLY DISINTEGRATING TABLET AND METHOD OF PREPARATION

An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegr...

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Bibliographic Details
Main Authors WANG, HONGFEI, LI, HEWEI, WANG, LINYUAN, WANG, MINGZHOU
Format Patent
LanguageEnglish
French
German
Published 30.03.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegrate rapidly in oral cavity and be taken without aid of water; Moreover, the formulation has a low hygroscopicity, so that the requirements for storing or producing the formulation is decreased, and the storage life is elongated to facilitate the administration by a patient and the preparation of the protein and vaccine drugs.
Bibliography:Application Number: EP20050752384