PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE

• Main Authors: LI, FRANCINE, FEIRONG, CAMPBELL, MICHAEL, GORDON, REHDER, KENNETH, S, VISCARDI, CELESTE, PATRICE, STRACHAN, JON-PAUL, GUO, ZHENGMING
• Format: Patent
• Language: English; French; German
• Published: 22.02.2012
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.