PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE

The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.

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Bibliographic Details
Main Authors LI, FRANCINE, FEIRONG, CAMPBELL, MICHAEL, GORDON, REHDER, KENNETH, S, VISCARDI, CELESTE, PATRICE, STRACHAN, JON-PAUL, GUO, ZHENGMING
Format Patent
LanguageEnglish
French
German
Published 22.02.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
AbstractList The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
Author VISCARDI, CELESTE, PATRICE
CAMPBELL, MICHAEL, GORDON
STRACHAN, JON-PAUL
REHDER, KENNETH, S
LI, FRANCINE, FEIRONG
GUO, ZHENGMING
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– fullname: STRACHAN, JON-PAUL
– fullname: GUO, ZHENGMING
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DocumentTitleAlternate PRENYLIERUNGSINHIBITOREN UND VERFAHREN ZU DEREN SYNTHESE UND ANWENDUNG
INHIBITEURS DE PRENYLATION ET LEURS METHODES DE SYNTHESE ET D'UTILISATION
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RelatedCompanies PHARMACO INVESTMENTS, INC
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Snippet The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE
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