HETEROARYL SUBSTITUTED PYRAZOLE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5
Pyrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar diso...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English French German |
Published |
22.09.2004
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Abstract | Pyrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases. |
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AbstractList | Pyrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases. |
Author | CHEN, CHIXU SMITH, NICHOLAS, D HU, ESSA HUANG, DEHUA MUNOZ, BENITO PRASIT, PETPIBOON COSFORD, NICHOLAS, D., P EASTMAN, BRIAN, W |
Author_xml | – fullname: HUANG, DEHUA – fullname: MUNOZ, BENITO – fullname: PRASIT, PETPIBOON – fullname: EASTMAN, BRIAN, W – fullname: COSFORD, NICHOLAS, D., P – fullname: HU, ESSA – fullname: CHEN, CHIXU – fullname: SMITH, NICHOLAS, D |
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DocumentTitleAlternate | MODULATEURS PYRAZOLE A SUBSTITUTION HETEROARYLE DU RECEPTEUR 5 METABOTROPIQUE DE GLUTAMATE HETEROARYL-SUBSTITUIERTE PYRAZOL-MODULATOREN DES METABOTROPEN GLUTAMATREZEPTORS-5 |
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SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | HETEROARYL SUBSTITUTED PYRAZOLE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 |
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