HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS

Compounds of formula (I) where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. Theses compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts i...

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Main Authors CANAN KOCH, STACIE S, BURKE, BENJAMIN J, KUCERA, DAVID J, VIRGIL, SCOTT C, BOYER, FREDERICK E, JEWELL, TANYA M, REICH, SIEGFRIED H, BARVIAN, MARK, ALEXANDER, THERESE N, MURPHY, SEAN T, HOLLER, TOD, MACHAK, JEFF, MITCHELL, LENNERT J, BOLTON, GARY, TATLOCK, JOHN H, WORLAND, STEPHEN T, MELNICK, MICHAEL, PRASAD JOSYULA, VARA, SKALITZKY, DONALD J, VARNEY, MICHAEL D
Format Patent
LanguageEnglish
French
German
Published 25.08.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula (I) where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. Theses compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
Bibliography:Application Number: EP20020744295