VASCULAR WALL-SELECTIVE ACAT INHIBITOR

• Main Authors: SHIBUYA, KIMIYUKI, YOSHINAKA, YASUNOBU, KITAMURA, TAKAHIRO, KAWAMINE, KATSUMI, YAMADA, YOUICHI, MIURA, TORU, OOGIYA, TADAAKI, EDANO, TOSHIYUKI
• Format: Patent
• Language: English; French; German
• Published: 15.09.2004
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

It is intended to provide a novel compound, which sustains an ACAT inhibitory activity and a macrophage-selectivity to a certain degree as a practically usable drug and can maintain an excellent oral absorption property and a favorable drug concentration in case of tested in vivo; a process for prod...