UROKINASE INHIBITORS
The invention relates to the compounds of general formula (I), that are present with respect to R as racemates as well as L- or D-configured compounds and as E/Z mixtures as well as E or Z isomers and in which the various symbols are defined as in the description and the claims, as well as to the sa...
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Main Author | |
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Format | Patent |
Language | English French German |
Published |
02.01.2004
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to the compounds of general formula (I), that are present with respect to R as racemates as well as L- or D-configured compounds and as E/Z mixtures as well as E or Z isomers and in which the various symbols are defined as in the description and the claims, as well as to the salts thereof, for use as therapeutic agents and for diagnostic purposes. The inventive compounds can be processed to medicaments or to diagnostic agents that are used for the diagnosis, therapy and prevention of urokinase- or urokinase-receptor associated diseases, for example for the treatment of tumors. The compounds are highly efficient in inhibiting growth and/or spread of malign tumors, for example tumor spread of pancreatic cancer, tumor growth of breast cancer and the formation of tumor metastases. The compounds of formula (I) and the salts thereof can be produced by conventional methods. |
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Bibliography: | Application Number: EP20020703436 |