6,7-Oxygenated steroids and uses related thereto

Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stere...

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Main Authors SHEN, YAPING, BURGOYNE, DAVID, L, PIERS, EDWARD, SALARI, HASSAN, LANGLANDS, JOHN, M, CHAU, JOSEPH, H.L, ROGERS, CHRISTINE
Format Patent
LanguageEnglish
French
German
Published 23.04.2003
Edition7
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stereochemistries such as 6 alpha and 7 beta oxygen substitution, and an alpha hydrogen at the 5 position in addition to having 6 alpha and 7 beta oxygen substitution. Steroids having 3,4-epoxy functionality are also disclosed. In addition, steroids having C17 pyran and delta -lactone functionality, with oxygen substitution at C6 and C7, or at C15, of the steroid nucleus, are disclosed.
Bibliography:Application Number: EP20020025269