O-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD

• Main Authors: WASHBURN, WILLIAM, N, SHER, PHILIP, M, WU, GANG
• Format: Patent
• Language: English; French; German
• Published: 01.02.2006
• Subjects: APPARATUS THEREFOR; CHEMISTRY; DERIVATIVES THEREOF; GENERAL METHODS OF ORGANIC CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SUGARS

whereinwhen Y isor heteroaryl;A is -O(CH2)m, S, -NH(CH2)m, or (CH2)n where n is 0-3 and m is 0-2;and R to R are as defined herein.A method is also provided for treating diabetes and related diseases employing an SGLT2 inhibiting amount of the above compound alone or in combination with one, two or m...