EFFERVESCENT HISTAMINE H2 ANTAGONIST COMPOSITION
A histamine H2 antagonist incompatible with acidic materials is incorporated in an effervescent composition and is stable therein provided the acidulant employed in the effervescent couple is a non-hydroxy group containing acidulant and such acidulant is employed as substantially the entire amount o...
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| Main Authors | , |
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| Format | Patent |
| Language | English French German |
| Published |
30.06.2004
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| Edition | 7 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | A histamine H2 antagonist incompatible with acidic materials is incorporated in an effervescent composition and is stable therein provided the acidulant employed in the effervescent couple is a non-hydroxy group containing acidulant and such acidulant is employed as substantially the entire amount of the acidulant present in the formulation. Preferably the composition is devoid of hydroxy group containing acidulant. Adipic acid, succinic acid, fumaric acid and succinic anhyride may be employed as the acidulant. Adipic acid is preferred. |
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| AbstractList | A histamine H2 antagonist incompatible with acidic materials is incorporated in an effervescent composition and is stable therein provided the acidulant employed in the effervescent couple is a non-hydroxy group containing acidulant and such acidulant is employed as substantially the entire amount of the acidulant present in the formulation. Preferably the composition is devoid of hydroxy group containing acidulant. Adipic acid, succinic acid, fumaric acid and succinic anhyride may be employed as the acidulant. Adipic acid is preferred. |
| Author | MIGTON, JOHN HUSSEIN, M., MAMOUN |
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| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | COMPOSITION EFFERVESCENTE CONTENANT DES ANTAGONISTES D'HISTAMINE H2 EINEN HISTAMIN H 2 ANTAGONISTEN ENTHALTENDE BRAUSEZUSAMMENSETZUNG |
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| Notes | Application Number: EP20000980395 |
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| RelatedCompanies | BRISTOL-MYERS SQUIBB COMPANY |
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| Snippet | A histamine H2 antagonist incompatible with acidic materials is incorporated in an effervescent composition and is stable therein provided the acidulant... |
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| Title | EFFERVESCENT HISTAMINE H2 ANTAGONIST COMPOSITION |
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