Microbial transformation process for hydroxyaromatic compounds

• Main Authors: TAKIGAWA, SHINICHIRO, YOSHIDA, TOYOKAZU, SUZUKI, HIDEO, NAGASAWA, TORU
• Format: Patent
• Language: English; French; German
• Published: 16.01.2002
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; SPIRITS; VINEGAR; WINE

The present invention provides a microbial transformation process for producing a hydroxyaromatic compound represented by the formula (II): wherein R represents carboxyl group, C2-5 alkoxycarbonyl group, hydroxyl group, nitro group, cyano group or C1-5 alkyl group, m is an integer of 1 to 5, n is an integer of 0 to 5, p is an integer of 1 to 3, m, n and p satisfy a relation of m+n</=4+2p, and when n is 2 or more, R may be the same or different from each other, which comprises bringing an aromatic sulfonic acid compound represented by the formula (I) : wherein each of R , m, n and p has the same meaning as defined above, and M represents hydrogen, alkali metal, alkaline earth metal or C1-5 alkyl group; in contact with a culture medium, cells, or treated cells of a microorganism belonging to Ochrobactrum genus, and Ochrobactrum anthropi S9 deposited under a receipt number of FERM BP-7546.