BETA-SHEET MIMETICS AND METHODS RELATING TO THE USE THEREOF

beta -sheet mimetics and methods relating to the same are disclosed. The beta -sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a beta -sheet mime...

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Bibliographic Details
Main Authors MCMILLIAN, MICHAEL, K, QABER, MAHER, N, TULINSKY, JOHN E, KAHN, MICHAEL, S, MATHEW, JESSYMOL
Format Patent
LanguageEnglish
French
German
Published 02.01.2003
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:beta -sheet mimetics and methods relating to the same are disclosed. The beta -sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a beta -sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase, transcription factor and/or protein-protein binding interaction.
Bibliography:Application Number: EP19980908551