HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES HAVING MMP AND TNF INHIBITORY ACTIVITY

Disclosed are hydroxamic and carboxylic acid derivatives which are useful inhibitors of matrix metalloproteinase and/or TNF alpha -mediated diseases, including degenerative diseases and certain cancers.

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Bibliographic Details
Main Authors KEILY, JOHN, FRASER, BAXTER, ANDREW, DOUGLAS, OWEN, DAVID, ALAN, WATSON, ROBERT, JOHN, MONTANA, JOHN, GARY
Format Patent
LanguageEnglish
French
German
Published 06.05.2004
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are hydroxamic and carboxylic acid derivatives which are useful inhibitors of matrix metalloproteinase and/or TNF alpha -mediated diseases, including degenerative diseases and certain cancers.
Bibliography:Application Number: EP19970935666