Process for the enzymatic separation of enantiomers of racemic 2-oxotricyclo-2,2,1,03,5-heptan-7-carboxylic acids and esters thereof

• Main Authors: HOLLA, WOLFGANG, BECK, GERHARD
• Format: Patent
• Language: English; French; German
• Published: 02.03.2005
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PROCESSES USING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Process for enzymic resolution (racemate or enantiomer sepn.) of enantiomer or racemic mixts. of oxo-tricyclo-heptane carboxylate cpds. of formula (I) comprises: (a) treating (I) with an enzyme (A) in water and opt. cosolvent and (b) sepg. acid and ester. (A) is a lipase or esterase derived from por...