Hydantoin derivatives, and their use in preventing and treating diabetic complications and circulatory organ diseases

Novel hydantoin derivatives have the following general formula (I): wherein A represents an oxygen or sulfur atom or the group B(CH2)pY in which B is CH or N, Y is a hydrogen atom, an aromatic ring or an alkyl or alkenoyl group, which may or may not be substituted by an aromatic ring, and p is 0, 1,...

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Main Authors HAYASHI, MOTOHIDE, SANWA KAGAKU, KENKYUSHO CO.LTD, KONDO, YASUAKI, SANWA KAGAKU, KENKYUSHO CO.LTD, KURONO, MASAYASU, SANWA KAGAKU, KENKYUSHO CO.LTD, NAKAMURA, SHIGEYOSHI, SANWA KAGAKU, KENKYUSHO CO, TANAKA, YUKIYA, SANWA KAGAKU, KENKYUSHO CO.LTD, USUI, TOSHINAO, SANWA KAGAKU, KENKYUSHO CO.LTD, MIURA, KENJI, SANWA KAGAKU, KENKYUSHO CO.LTD, SUZUKI, TUNEMASA, SANWA KAGAKU, KENKYUSHO CO.LTD, TOMIYA, NOBORU, SANWA KAGAKU, KENKYUSHO CO.LTD, SAWAI, KIICHI, SANWA KAGAKU, KENKYUSHO CO.LTD
Format Patent
LanguageEnglish
French
German
Published 13.05.1992
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel hydantoin derivatives have the following general formula (I): wherein A represents an oxygen or sulfur atom or the group B(CH2)pY in which B is CH or N, Y is a hydrogen atom, an aromatic ring or an alkyl or alkenoyl group, which may or may not be substituted by an aromatic ring, and p is 0, 1, 2 or 3, X represents a halogen atom, and m and n, which may be identical or different, are each 1, 2 or 3. The components (I) and their salts are efficacious against diabetic complications and circulatory organ diseases.
Bibliography:Application Number: EP19910310320